Categories for Vets-News

Enantiomer-specific effects of albuter...

Date: 4th Jul 2018
Posted By: Jon Slattery

  Reinero et al. discuss the hypothesis that regular administration of R,S-albuterol or S-albuterol, but not R-albuterol, would induce airway inflammation in healthy and asthmatic cats. Racemic (R,S)-albuterol is a 1:1 mixture of an R-enantiomer which has bronchodilatory and anti-inflammatory effects, and an S-enantiomer which is associated with increased airway hyperreactivity and proinflammatory effects. Proinflammatory... Read More

Bioavailability and tolerability of ne...

Date: 4th Jul 2018
Posted By: Jon Slattery

  Haspel et. al compare the pharmokinetics and bioavailability of dexamethasone sodium phosphate (DSP) given by the intravenous and nebulised route. Their findings support similar studies in humans showing that efficacy between the two routes at reducing neutrophil counts in BAL is similar but plasma concentrations are much less via the nebulised route. This study... Read More

Scintigraphic Assessment of Deposition...

Date: 17th Oct 2017
Posted By: Jon Slattery

K. Chow et al. from the University of Melbourne compare the efficacy of radiolabeled fluticasone using a metered dose inhaler and by nebulisation. Percentage deposition in the lower airways was lower than that reported in adult humans but similar to that reported in children. nebulisation achieved approximately 60% higher concentrations within the lower airways compared... Read More

Superiority of Nebulized Corticosteroi...

Date: 27th Nov 2014
Posted By: Jon Slattery

Mitsuhiro Kamimura et al. discuss why nebulisation is superior to particle based inhalers in certain patients with cough variant asthma. This study may have relevance to canine patients with primarily upper respiratory tract airway inflammation. Read the full article Allergology International. 2012;61411-417 Read More

Feline asthma – a review and new ins...

Date: 14th Nov 2014
Posted By: Jon Slattery

R.A. Hirt presents a comprehensive review of both the current understanding and treatment protocols of feline asthma. The article also goes on to discuss current research into the disease and gives a preview of future therapeutics. Read the full article(187Kb) here… This paper was originally printed in German in Wien.Tierarztl.Mschr Vol 90 110-123 ,and subsequently... Read More

Management of 13 cases of canine respi...

Date: 14th Nov 2014
Posted By: Jon Slattery

Journal of Small Animal Practice 2006 47 (7): 377-382 Bexfield, N.H., Foale, R.D., Davison, L.J., Watson, P.J., Skelly, B.J., and Herrtage, M.E. Abstract: Bexfield et al discuss the value of using inhaled corticosteroids in the management of chronic inflammatory airway disease in dogs. Thirteen dogs that fulfilled the criteria were identified. Ten dogs were diagnosed... Read More

Investigation and treatment of feline ...

Date: 14th Nov 2014
Posted By: Jon Slattery

Mardell, E., (2007). Investigation and treatment of feline chronic bronchial disease. In Practice March 2007;29 (3):138-146 Domestic cats presenting with a chronic cough or wheeze are encountered with some frequency in small animal practice. The problem may be persistent or episodic, and can vary widely in severity. Clinically, many cases resemble human chronic bronchial disease... Read More

Summary of current therapeutic rationa...

Date: 14th Nov 2014
Posted By: Jon Slattery

The AeroKat Feline Aerosol Chamber and AeroDawg Canine Aerosol Chamber are designed to be used along with metered dose inhalers (MDIs) to deliver aerosol medication to animals suffering from respiratory diseases. When the chamber is attached to the MDI it allows the animal to breathe normally and inhale the aerosol medication. Both chambers include a... Read More